Table 2.

Relative transcript levels of HSV-1 receptors in adult human hippocampus versus cerebellum

Database	ABA			HBT
Gene	Fold change scorea	Mean fold change	P valuea	Mean fold changeb	P valueb
Controls
NR3C2	3.33c	3.25	8.21E−80	1.85	<0.001
	3.17c		1.53E−74
GAPDH	1.04	1.04	ns	nd	na
GAPDH2	na	na	na	0.98	ns
HSV receptors
MAG	ne	ne	na	2.90	<0.001
MYH9	2.15	2.07	1.92E−44	1.99	<0.001
	1.98		5.01E−57
PILRA	ne	ne	na	ne	na
PVRL1	4.04	3.06	1.11E−46	1.40	<0.001
	2.59		5.62E−38
	2.54		4.55E−38
TNFRSF14	2.49	1.84	4.39E−56	nd	nd
	1.18		5.84E−03

ABA Allan Brain Atlas, HBT Human Brain Transcriptome database, na not applicable, nd no data, ns not significant, ne not enriched in hippocampus

^aFold change overexpression scores were determined by comparing levels of gene expression in Hpc versus a control brain region (cerebellum, Cb); P values and fold change scores were computed online at ABA

^bFold change overexpression scores are for adult Hpc versus cerebellar cortex and are means of values for age-points 10,000 days (adult) and 30,000 days only (elderly adult); P values for Hpc versus cerebellar cortex, Student t test

^cDifferent entries for each gene correspond to different hybridization probes for the same target (cf Fig. 1)