Table 2.
Pathway enrichment analysis of AS genes in E. granulosus and E. multilocularis.
| Pathway ID | Description |
E. granulosus |
P-value |
E. multilocularis |
P-value | ||
|---|---|---|---|---|---|---|---|
| All genes | AS genes | All genes | AS genes | ||||
| Cellular processes | |||||||
| ko04111 | Cell cycle – yeast | 45 | 22 | 2.16E - 02 | 50 | 31 | 1.67E - 04 |
| ko04113 | Meiosis – yeast | 40 | 21 | 9.36E - 03 | 46 | 25 | 8.56E - 03 |
| Environmental information processing | |||||||
| ko04070 | Phosphatidylinositol signaling system | 25 | 16 | 1.62E - 03 | 26 | 22 | 4.90E - 07 |
| ko04630 | Jak-STAT signaling pathway | 12 | 9 | 3.82E - 03 | 11 | 8 | 1.50E - 02 |
| ko04370 | VEGF signaling pathway | 22 | 13 | 1.15E - 02 | 23 | 15 | 4.24E - 03 |
| ko04330 | Notch signaling pathway | 15 | 9 | 3.06E - 02 | 13 | 10 | 3.26E - 03 |
| ko04090 | Cellular antigens | 29 | 15 | 3.08E - 02 | 28 | 18 | 2.22E - 03 |
| Genetic information processing | |||||||
| ko03022 | Basal transcription factors | 26 | 14 | 2.45E - 02 | 25 | 17 | 1.17E - 03 |
| ko03015 | mRNA surveillance pathway | 55 | 30 | 9.30E - 04 | 53 | 31 | 7.20E - 04 |
| ko03013 | RNA transport | 92 | 48 | 1.38E - 04 | 87 | 47 | 4.58E - 04 |
| Metabolism | |||||||
| ko00510 | N-glycan biosynthesis | 30 | 20 | 1.88E - 04 | 30 | 23 | 6.78E - 06 |
| ko00562 | Inositol phosphate metabolism | 20 | 13 | 3.67E - 03 | 20 | 18 | 8.70E - 07 |
| ko00513 | Various types of N-glycan biosynthesis | 26 | 18 | 1.92E - 04 | 23 | 17 | 2.47E - 04 |
| ko00071 | Fatty acid metabolism | 10 | 7 | 1.95E - 02 | 10 | 7 | 3.09E - 02 |
| ko00280 | Leucine and isoleucine degradation | 7 | 6 | 6.82E - 03 | 8 | 6 | 2.96E - 02 |
| ko00052 | Galactose metabolism | 19 | 11 | 2.38E - 02 | 19 | 11 | 4.33E - 02 |
| ko00640 | Propanoate metabolism | 12 | 9 | 3.82E - 03 | 13 | 9 | 1.56E - 02 |
| ko00563 | GPI-anchor biosynthesis | 17 | 11 | 7.92E - 03 | 16 | 10 | 2.85E - 02 |
| ko00061 | Fatty acid biosynthesis | 3 | 3 | 3.69E - 02 | 3 | 3 | 4.70E - 02 |
| ko00561 | Glycerolipid metabolism | 18 | 13 | 8.38E - 04 | 20 | 13 | 8.04E - 03 |
| ko00230 | Purine metabolism | 84 | 41 | 2.26E - 03 | 86 | 41 | 1.77E - 02 |
| Organismal systems | |||||||
| ko04380 | Osteoclast differentiation | 17 | 11 | 7.92E - 03 | 16 | 10 | 2.85E - 02 |
| ko04664 | Fc epsilon RI signaling pathway | 17 | 10 | 2.71E - 02 | 16 | 11 | 8.04E - 03 |
| ko04912 | GnRH signaling pathway | 26 | 13 | 4.78E - 02 | 31 | 17 | 2.52E - 02 |
| ko04660 | T cell receptor signaling pathway | 31 | 17 | 1.09E - 02 | 31 | 18 | 1.03E - 02 |
| ko04620 | Toll-like receptor signaling pathway | 14 | 10 | 4.00E - 03 | 14 | 10 | 7.72E - 03 |