Fig. 8.

Lower numbers of selected hematopoietic stem and progenitor cell populations in spleens of Hmox1^−/− mice 21 days after MI. Flow cytometric analysis of a SKL cells (CD45⁺ Sca-1⁺ c-kit⁺ Lin⁻), b long-term HSC (LT-HSC; CD45⁺ Sca-1⁺ c-kit⁺ Lin⁻ CD34⁻ CD48⁻ CD150⁺), c short-term HSC (ST-HSC; CD45⁺ Sca-1⁺ c-kit⁺ Lin⁻ CD34⁺ CD48⁻ CD150⁺), d hematopoietic progenitors (HPC; CD45⁺ Sca-1⁺ c-kit⁺ Lin⁻ CD34⁺ CD48⁻ CD150⁻), e multipotent hematopoietic progenitors (MPP; CD45⁺ Sca-1⁺ c-kit⁺ Lin⁻ CD34⁺ CD48⁺ CD150⁻), f progenitor cells lacking Sca-1 (KL; CD45⁺ Sca-1⁻ c-kit⁺ Lin⁻) and g granulocyte-monocyte progenitor cells (GMP; CD45⁺ Sca-1⁻ c-kit⁺ Lin⁻ CD34⁺ CD48⁺⁺ CD150⁻) in the spleens of mice after LAD ligation or sham surgery (5–10 mice/group). Data represented as a number of cells per spleen. *p < 0.05, **p < 0.01, ***p < 0.0001