Table 2.
Alaskan berry and fungus treatments extend wildtype C. elegans lifespan.
Treatment | N | Mean lifespan ± S.E.M. | Percent of control (%) | p-value | Highest increase observed (%) | Lowest increase observed (%) |
---|---|---|---|---|---|---|
Blueberry dose (μg/mL) | ||||||
0 | 60 | 9.48 ± 0.31 | ||||
60 | 66 | 12.4 ± 0.56 | 130 | <0.0001 | 128 | 107 |
100 | 60 | 11.2 ± 0.59 | 118 | <0.0001 | 144 | 111 |
200 | 51 | 12.4 ± 0.73 | 130 | 0.001 | 147 | 120 |
400 | 58 | 11.2 ± 0.58 | 118 | <0.0001 | 139 | 120 |
800 | 60 | 9.31 ± 0.28 | 98 | 0.341 | 117 | 109 (n.s.) |
Lowbush cranberry dose (μg/mL) | ||||||
0 | 50 | 11.3 ± 0.58 | ||||
50 | 50 | 13.9 ± 0.91 | 123 | 0.012 | 122 | 116 |
100 | 51 | 11.1 ± 0.50 | 98 | 0.868 | 116 | 104 (n.s.) |
200 | 50 | 12.5 ± 0.49 | 110 | 0.123 | 119 | 106 |
400 | 50 | 13.9 ± 0.89 | 123 | 0.016 | 122 | 108 |
800 | 50 | 12.5 ± 0.28 | 110 | 0.229 | 119 | 108 (n.s) |
Chaga dose (μg/mL) | ||||||
0 | 50 | 10.7 ± 0.50 | ||||
50 | 49 | 13.1 ± 0.60 | 122 | 0.002 | 122 | 113 |
200 | 50 | 12.9 ± 0.55 | 121 | 0.005 | 124 | 117 |
800 | 47 | 12.9 ± 0.65 | 121 | 0.003 | 121 | 116 |
Percent change in lifespan relative to control, significance from the representative survival curves shown in Figures 1A–C. The highest and lowest percent increase in lifespan relative to control in all replicates is also reported. Experiments were repeated in multiple independent trials (≥3), all with the same directional effect and similar magnitude of effect. Statistical significance (p-value) calculated with Kaplan-Meier log-rank test.