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Restoration of dystrophin-associated proteins. (Left) Muscle of control mdx mouse. (Right) Muscle of mdx mouse after triple tail-vein injections of the 2OMeAO at weekly intervals. Membrane localized α-sarcoglycan, β-dystroglycan and neuronal nitric oxide synthase (nNOS) are detected in the fibers expressing dystrophin after the 2OMeAO treatment. Nuclei were counterstained with 4′,6-diamidino-2-phenylindole (blue).
