Table 1.
Epidemiological, clinical, and radiological characteristics of the 46 included patients.
| Value | N | |
|---|---|---|
| Sex ratio (male/female) | 4 | 42 |
| Median age, years (range) | 40.5 [12–66] | 38 |
| Median delay between cART and IRIS, days (range) | 38 [18–120] | 33 |
| Unmasking PML-IRIS | 41 [20–120] | 14 |
| Paradoxical PML-IRIS | 38 [18–120] | 19 |
| Clinical features | ||
| Motor deficit (%) | 27 (69%) | 39 |
| Speech disorders (%) | 14 (36%) | 39 |
| Cognitive disorders (%) | 13 (33%) | 39 |
| Cerebellar ataxia (%) | 11 (28%) | 39 |
| Visual disturbances (%) | 9 (23%) | 39 |
| Facial paralysis (%) | 4 (10%) | 39 |
| Seizure (%) | 3 (8%) | 39 |
| Brain MRI abnormalities | ||
| Hypo intense lesions on T1-weighted and hyper intense lesions on T2-weighted and FLAIR sequences (%) | 35 (76%) | 46 |
| Contrast-enhanced lesions (%) | 40 (87%) | 46 |
| Edema (%) | 14 (30%) | 46 |
| Mass effect (%) | 11 (24%) | 46 |
N: number of data available for characteristic.