Table 2. Effect of structural noise on relative orientations and changes therein of the terminal regions of native and modified Dickerson dodecamers.

DNA oligomer	α, °	β, °	γ, °
Native†	1.3 ± 3.2	1.0 ± 5.0	–1 ± 14
T8*	–2.4 ± 3.9	0.6 ± 3.8	10 ± 10
T8*-native†	–3.7 ± 1.6	–0.5 ± 2.9	11 ± 15
Native†	0.6 ± 3.0	1.3 ± 5.3	11 ± 22
T7*	–8.6 ± 1.9	1.8 ± 3.8	2 ± 13
T7*-native‡	–9.3 ± 1.7	0.5 ± 2.7	–9 ± 12
Native†	1.6 ± 3.2	1.6 ± 4.7	3 ± 24
T7*T8*	–12.7 ± 3.5	0.9 ± 3.8	17 ± 9
T7*T8*-native‡	–14.2 ± 1.6	–0.7 ± 3.0	14 ± 22

^†Average and standard deviation of RDC-derived rotation angles between the terminal domains of the structure of the native dodecamer (PDB entry 1NAJ) and a set of 20 noise-contaminated reference structures. Only RDCs in the terminal three base pairs (terminal four base pairs for T7^*) that were measured in both the native and modified oligomer are used to define the rotation angles

^‡Average and standard deviation of pairwise difference in rotation angles obtained from data measured for modified and native dodecamers, for a set of 20 noise-contaminated reference structures