TABLE 2.

SH2 domain-containing adaptor proteins bind directly to a CD6 pY629 peptide^a

Peptide	KD (μM)
	GADS SH2	GRB2 SH2	TSAd SH2
CD6 pY629	1–3	2–4	26–58
CD28 pYMN	2–3	3	74b

^aThe K_D was determined from equilibrium binding of soluble recombinant SH2 domains to the immobilized peptide at 37°C by using SPR (n = 3).

^bn = 1.