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. 2017 Apr 21;19:91–97. doi: 10.1016/j.ebiom.2017.04.025

Table 2.

IgA seroreactivity to FlaB-mV or C6.

FlaB-mVa
 C6b
Diagnosis Positive Equivocal Negative Total Positive Equivocal Negative Total
Early Lyme (n = 152) 53 (34.9%) 5 (3.3%) 94 (61.8%) 152 43 (28.3%) 11 (7.2%) 98 (64.5%) 152
Late Lyme (n = 19) 6 (31.6%) 2 (10.5%) 11 (57.9%) 19 3 (15.8%) 2 (10.5%) 14 (73.7%) 19
Normal (non-endemic) (n = 104) 1 (0.9%) 3 (2.8%) 100 (96.2%) 104 1 (0.9%) 3 (2.8%) 100 (96.2%) 104
Normal (endemic) (n = 35) 1 (2.9%) 2 (5.7%) 32 (91.4%) 35 1 (2.9%) 1 (2.9%) 33 (94.3%) 35
Rheumatoid arthritis (n = 53) 0 (0.0%) 1 (1.9%) 52 (98.1%) 53 1 (1.9%) 0 (0.0%) 52 (98.1%) 53
Syphilis (n = 34) 1 (2.9%) 2 (5.9%) 31 (91.2%) 34 1 (2.9%) 0 (0.0%) 33 (97.1%) 34
Fibromyalgia (n = 16) 0 (0.0%) 0 (0.0%) 16 (100.0%) 16 0 (0.0%) 0 (0.0%) 16 (100.0%) 16
a

Fisher's exact test of positive vs. non-positive (equivocal + negative) IgA levels (alpha < 0.05) for each indicated group: early Lyme vs. nonendemic normals (p < 0.0001); early Lyme vs. endemic normals (p < 0.0001); early Lyme vs. syphilis (p < 0.0001); early Lyme vs. RA (p < 0.0001); early Lyme vs. fibromyalgia (p < 0.005), early Lyme vs. late Lyme n.s.; late Lyme vs. nonendemic normals (p < 0.0001).; late Lyme vs. endemic normals (p < 0.01).; late Lyme vs. syphilis (p < 0.01); late Lyme vs. RA (p < 0.005); late Lyme vs. fibromyalgia (p < 0.05). n.s. = not significant.

b

Fisher's exact test of positive vs. non-positive (equivocal + negative) IgA levels (alpha < 0.05) for each indicated group: early Lyme vs. nonendemic normals (p < 0.0001); early Lyme vs. endemic normals (p < 0.001); early Lyme vs. syphilis (p < 0.001); early Lyme vs. RA (p < 0.0001); early Lyme vs. fibromyalgia (p < 0.05); early Lyme vs. late Lyme n.s; late Lyme vs. nonendemic normals (p < 0.05); late Lyme vs. endemic normals n.s.; late Lyme vs. syphilis n.s.; late Lyme vs. RA n.s.; late Lyme vs. fibromyalgia n.s. n.s. = not significant.