TABLE 7.
Infection of U87 cells: control variants
| Variant | Referenceb | Phenotypec | RT concna
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Parental | CCR1 | CCR2b | CCR3 | CCR5 | CXCR4 | CXCR6 | |||
| HIV-2 | |||||||||
| MIR | 37 | R1R2R3R5X4 | 78 | 287 | 108 | 47,267 | 10,059 | >61,730 | 9,412 |
| prCBL20 | 37 | R1R2R3R5X4 | 205 | 94 | 78 | 287 | 189 | >61,730 | 39,175 |
| PH2-1 E6 | 29 | R1R3R5X4 | 41,785 | 49,719 | 6,748 | 33,023 | 48,376 | >61,730 | 17,696 |
| RH2-5 E4 | 29 | R1R3R5X4 | 28,740 | >61,730 | 667 | >61,730 | >61,730 | 17,763 | >61,730 |
| HIV-1 | |||||||||
| ACH337 9.2F4 | 45 | R5 | 48 | − | − | − | 7,581 | − | − |
| ACH583 9.2A2 | 45 | R5 | 541 | − | − | − | 25,480 | − | − |
| ACH39 *H4 | 55 | R3X4 | − | − | − | 25,209 | − | 30,508 | − |
| ACH208 *4C8 | 55 | X4 | − | − | − | − | − | >31,055 | − |
a
See legend to Table 6.
b
Study previously describing coreceptor use of the variants indicated.
c
Phenotypes of the variants as established in the studies indicated; the abbreviations R1, R2, R3, R5, and X4 represent the different chemokine receptors used.