TABLE 5.

Correlation between discordant resistance, env sequence partitioning, and neurocognitive impairment^a

Parameter	Any Rx	Discordant resistance	V3 sequence partitioning	C2-V3 signature	Nadir CD4 >200	Current CD4 >100	Plasma RNA >105	CSF RNA >104
Discordant resistance	NS		0.035 (α)	0.007 (α)	0.09 (α−1)	NS	NS	NS
V3 sequence partitioning	0.09 (α)	0.035 (α)		0.008 (α)	NS	NS	NS	0.10 (α−1)
Neurocognitive function (GDS)	NS	0.07 (α)	NS	NS	0.05 (α−1)	NS	NS	NS

^aData are P values for correlation between discordant resistance and env sequence partitioning (using Fisher's exact test) and neurocognitive impairment (using Welch's analysis of variance) with clinical and virological parameters. CD4 levels are reported in cells per cubic millimeter; RNA levels are reported in log copies per milliliter. NS, not significant; α, direct correlation; α⁻¹, inverse correlation.