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. 2017 May 22;17:36. doi: 10.1186/s12894-017-0226-2

Table 3.

Change of treatment in men initially prescribed an α-blocker plus an antimuscarinic combination treatment and non-persistent at 12 months

FDC Concomitant therapy
Change of treatment in men non-persistent at 12 months, N (%) N = 324 N = 859
 Switcha 19 (5.9) 56 (6.5)
 No switch/discontinuationb 305 (94.1) 803 (93.5)
Switched to, N (%) N = 19 N = 56
 Combination with new α-blocker 1 (5.3) 5 (8.9)
 Combination with new antimuscarinic 6 (31.6) 25 (44.6)
 Concomitant therapy with the same drugs 9 (47.4) 3 (5.4)
 Concomitant therapy with a new α-blocker and antimuscarinic 3 (15.8) 0
 FDC 0 23 (41.1)
No switch/discontinuation, N (%) N = 305 N = 803
 α-blocker therapy only 58 (19.0) 246 (30.6)
 Antimuscarinic therapy only 19 (6.2) 107 (13.3)
 No therapy changes 228 (74.8) 450 (56.0)

FDC fixed-dose combination

aAlternative combination therapy prescribed within 30 days following discontinuation of index combination therapy

bNo alternative combination therapy prescribed within 30 days following discontinuation of index combination therapy