Table 2.
Histological parameters and semi-quantitative scoring system for day 2 wounds
| Scale | Epithelialization | PMNL a | MM b | Fibroblasts | Endothelial cell activity |
|---|---|---|---|---|---|
| 0 | No proliferation at wound edge | No or very few cells present | No or very few cells present | No or very few plump fibroblasts present | No vessels with plump endothelial cells |
| 1 | Hyperplasia/hypertrophy at wound edge | Few cells or focal pattern, ≤40% of total cellularity | ≤20% of total cellularity | ≥50% spindle cells, ≤50% plump fibroblasts | ≤50% vessels with plump endothelial cells |
| 2 | Migration of cells over wound bed | Numerous cells present in all layers, ≥40% of total cellularity | ≥20% of total cellularity | ≥50% plump fibroblasts, ≤50% spindle cells | ≥50% vessels with plump endothelial cells |
apolymorphonuclear leukocytes; bmonocytes/tissue macrophages