Table 4.

Likelihood of treatment compliance in patients initiating an oral bisphosphonate.

	MPR ≥ 60%a			MPR ≥ 80%a
	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value
On-treatment GI events	0.84	0.73–0.97	0.016	0.91	0.79–1.06	0.234
Pre-treatment GI events	1.01	0.86–1.18	0.917	1.11	0.94–1.30	0.221
Age group (reference 55–64)			< 0.001			< 0.001
65–74	0.94	0.81–1.10		0.96	0.83–1.12
75–84	0.99	0.85–1.15		0.93	0.80–1.09
≥ 85	0.98	0.80–1.22		0.86	0.69–1.08
Pre-treatment medication use
Gastroprotective agents	1.00	0.88–1.14	0.940	1.03	0.90–1.18	0.970
NSAIDs	1.15	1.04–1.27	0.009	1.10	0.99–1.23	0.069
Pre-treatment OP-related fractures	1.21	1.01–1.45	0.036	1.13	0.95–1.36	0.172
Deyo-Charlson comorbidity index	0.94	0.90–0.99	0.009	0.94	0.90–0.99	0.015

CI, confidence interval; GI, gastrointestinal; MPR, medication possession ratio; NSAIDs, non-steroidal anti-inflammatory drugs; OP, osteoporosis.

^aBold font indicates statistical significance.