FIG. 1.

Inhibition of the PV-induced CPE in neural cells by MAb against PV or hPVR. Neural cells (A, B, C, D, and E) or HeLa cells (F, G, H, I, and J) were infected with PV1/Mahoney at an MOI of 10 (mock infection in panels A and F). At 2 hpi, the cells were washed three times. Then, medium not supplemented with MAbs (A, B, F, and G) or medium supplemented with MAbs against both PV1/Mahoney and PV1/Sabin (C and H), against hPVR (D and I), or against PV1/Sabin (E and J) was added to the culture. PV-infected cells were observed 24 hpi by microscopy.