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. 2017 May 22;18:14. doi: 10.1186/s12867-017-0092-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Atp2b2 genomic region adapted from the UCSC genome browser. Image exported from UCSC genome browser (NCBI37/mm9), data is from the Encyclopedia of DNA elements (ENCODE) consortium [22, 23]. Atp2b2 transcripts are shown in blue. a The whole genomic region surrounding Atp2b2 is shown. Marks for transcriptional modulation are shown in 8 week mouse cerebellum vs 8 week mouse heart tissue. The RNA-Sequencing (RNA-Seq) data suggests that both the α and β transcripts of Atp2b2 are expressed in the cerebellum. Neither transcript appears to be expressed in the heart. Both the α and β transcripts of Atp2b2 have a CpG island at their TSSs. Markers of active transcription (DHS, RNA Pol II and H3K4me3) are present in the cerebellum (shown as a heat map) but are not present in the heart. b The region surrounding the αAtp2b2 TSS is enlarged to show detail [23]