Table 2.
Correlation between plasma levels of EGFL6 and clinicopathological parameters in 392 OSCC patients.
| No. of case (%) | EGFL6 level | p value | |
|---|---|---|---|
| Variables | n = 392 | Mean ± S.D. (pg/mL) | |
| Age (years) | |||
| <55 | 182 (46.4%) | 303.25 ± 192.82 | 0.907 |
| ≥55 | 210 (53.6%) | 305.55 ± 196.49 | |
| Gender | |||
| male | 385 (98.2%) | 304.81 ± 195.85 | 0.802 |
| female | 7 (1.8%) | 286.17 ± 105.22 | |
| Smoking status | |||
| No | 46 (11.7%) | 283.02 ± 135.87 | 0.427 |
| Yes | 346 (88.3%) | 307.33 ± 201.04 | |
| Drinking status | |||
| No | 190 (48.5%) | 314.45 ± 191.09 | 0.326 |
| Yes | 202 (51.5%) | 295.10 ± 197.76 | |
| Betel nuts chewing | |||
| No | 85 (21.7%) | 275.86 ± 140.22 | 0.126 |
| Yes | 307 (78.3%) | 312.40 ± 206.58 | |
| Stage | |||
| I+II | 170 (43.4%) | 280.63 ± 186.88 | 0.033* |
| III+IV | 222 (56.6%) | 322.74 ± 198.71 | |
| Tumor T status | |||
| T1+ T2 | 233 (59.4%) | 279.74 ± 175.98 | 0.002* |
| T3+T4 | 159 (40.6%) | 340.73 ± 214.39 | |
| Lymph node status | |||
| N0 | 253 (64.5%) | 297.42 ± 185.82 | 0.333 |
| N1+N2+N3 | 139 (35.5%) | 317.34 ± 209.59 | |
| Metastasis | |||
| M0 | 390 (99.5%) | 302.19 ± 191.46 | 0.001* |
| M1 | 2 (0.5%) | 751.21 ± 371.22 | |
| Cell differentiation | |||
| Well differentiated | 57 (14.5%) | 338.69 ± 39.65 | 0.151 |
| Moderately or poorly differentiated | 335 (85.2%) | 298.66 ± 170.44 |
*p<0.05.