Table 2.

ICH vs. non-ICH cohorts: demographics, pre-admission morbidity, pre-cannulation SOFA score, ECMO mode, and indication

Variable	ICH cohort (n = 54)	Non-ICH cohort (n = 199)	p value
Demographics
Age (years)	51.5 (40–61)	50 (32–60)	0.158
Male sex	35 (65%)	127 (64%)	1.000
Pre-admission morbidity
Hypertension	9 (17%)	36 (18%)	0.967
Insulin-dependent diabetes mellitus	5 (9%)	22 (11%)	0.896
Chronic renal disease	2 (4%)	1 (1%)	0.116
Antithrombotic therapy	7 (13%)	7 (4%)	0.018
Charlson comorbidity index	0 (0–1)	0 (0–1)	0.373
Pre-cannulation SOFA score
Total	14 (10.8–16) (26 missing, 48%)	13 (10–15) (106 missing, 53%)	0.443
Respiration	4 (4–4) (25 missing, 46%)	4 (4–4) (95 missing, 48%)	0.340
Coagulation	2 (0–3) (26 missing, 48%)	1 (0–2) (100 missing, 50%)	0.015
Liver	1 (0–2) (26 missing, 48%)	1 (0–2) (102 missing, 51%)	0.960
Cardiovascular	4 (3–4) (25 missing, 46%)	4 (3–4) (95 missing, 48%)	0.742
Neurological	1 (0–2) (25 missing, 46%)	1 (0–2) (98 missing, 49%)	0.726
Renal	1.5 (1–4) (26 missing, 48%)	1 (0–4) (101 missing, 51%)	0.606
ECMO Indication
Pulmonary	48 (89%)	176 (88%)
Cardiac	2 (4%)	17 (9%)
ECPR	4 (7%)	6 (3%)
ECMO mode
Venovenous	31 (57%)	130 (65%)	0.361
Venoarterial	23 (43%)	69 (35%)	0.361

Values are expressed as median (interquartile range) or numbers (proportion)

Italicized text in the p value column indicates a statistically significant correlation (p < 0.05)

Pulmonary indications included pneumonia (n = 102), sepsis (n = 78), respiratory failure (n = 18), ARDS (n = 17), trauma (n = 6), and drowning (n = 3). Cardiac indications included cardiogenic shock (n = 18) and pulmonary embolism (n = 1)

Abbreviations: SOFA Sepsis-related Organ Failure Assessment (also known as Severity Organ Failure Assessment), ECMO extracorporeal membrane oxygenation, ICH intracranial hemorrhage, ECPR extracorporeal cardiopulmonary resuscitation