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. 2017 May 22;11:11. doi: 10.1186/s40246-017-0107-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Benchmarking analyses combining prioritizing strategies. Bar charts show the percentage of shared variants for hearing loss (a) and CNM (b), ranked by PAVAR + VAAST (purple), Exomiser v2 + (VAAST-Phevor) (yellow), the three systems (green) the three systems and CADD (red), and the three systems and FATHMM (blue) among the top 10, 20, or 50, after filtering by different control datasets. F = family controls exome dataset, T-F = in-house control data exome dataset without family control dataset, and T = in-house and family control datasets