Table 6.
Clinically significant neuropsychiatric symptoms at admission to nursing homes (NH)
| Prevalence of CS-NPS | All patients Total N=696 | Patients with dementia Total N=583 | Patients without dementia Total N=113 | p-value |
|---|---|---|---|---|
| n/N | n/N | n/N | ||
| Delusions | 97/686 (14.1) | 90/575 (15.7) | 7/111 (6.3) | 0.010a) |
| Hallucinations | 34/688 (4.9) | 33/576 (5.7) | 1/112 (0.9) | 0.031a) |
| Agitation | 99/689 (14.4) | 93/577 (16.1) | 6/112 (5.4) | 0.003a) |
| Depression | 148/688 (21.5) | 125/576 (21.7) | 23/112 (20.5) | 0.784a) |
| Anxiety | 141/690 (20.4) | 126/578 (21.8) | 15/112 (13.4) | 0.043a) |
| Euphoria | 23/687 (3.3) | 21/567 (3.6) | 2/111 (1.8) | 0.562b) |
| Apathy | 109/687 (15.9) | 95/575 (16.5) | 14/112 (12.5) | 0.287a) |
| Disinhibition | 101/687 (14.7) | 92/575 (16.0) | 9/112 (8.0) | 0.029a) |
| Irritability | 122/684 (17.8) | 110/572 (19.2) | 12/112 (10.7) | 0.031a) |
| Aberrant Motor Behaviour | 73/687 (10.6) | 69/575 (12.0) | 4/112 (3.6) | 0.008a) |
| Night-time Behaviour | 112/689 (16.3) | 98/577 (17.0) | 14/112 (12.5) | 0.239a) |
| Eating Change | 71/688 (10.3) | 58/576 (10.1) | 13/112 (11.6) | 0.625a) |
| Any symptom | 413/682 (60.6) | 359/571 (62.9) | 54/111 (48.6) | 0.005a) |
| NPI 12 sum median (range) | n=693 8.0 (0 - 123) | n=581 10.0 (0 - 123) | n=112 4.0 (0 - 66) | <0.001c) |
| NPI-AGITATION median (range) | n=678 1.0 (0 - 36) | n=566 1.0 (0 - 36) | n=112 0.0 (0 - 36) | <0.001c) |
| NPI-PSYCHOSIS median (range) | n=683 0.0 (0 - 24) | n=572 0.0 (0 - 24) | n=111 0.0 (0 - 12) | <0.001c) |
| NPI-AFFECTIVE median (range) | n=687 1.0 (0 - 24) | n=575 1.0 (0 - 24) | n=112 0.5 (0 - 24) | 0. 125c) |
All figures in (%) if not otherwise stated
CS-NPS - clinically significant NPS, defined as an NPI sub-symptom of 4 and above
NPI 12 sum - Neuropsychiatric Inventory sum of 12 items
NPI-AGITATION sum of agitation/aggression, disinhibition, and irritability
NPI-PSYCHOSIS sum of delusion and hallucination
NPI-AFFECTIVE sum of depression and anxiety
a) Pearson Chi-square test
b) Fisher’s Exact Test
c) Mann-Whitney U test