Table 3.
Genes with alleles specific to Cluster 1 isolates
| Locus | Functional category | Number of mutation | Number of non-synonymous mutation |
|---|---|---|---|
| NEIS2150 (alx/TerC) | Integral membrane protein (tellurite resistance protein) | 1 (bp 676) | 1 (A → S)a |
| NMAA_0255 | Insertion element IS1016 transposase | 1 (bp 28) | 1 (T → A)a |
| NEIS0947 (trpG) | Amino acid metabolism (phenylalanine, tyrosine and tryptophan biosynthesis) | 1 (bp 414) | 0 |
| NMAA_0798 | Hypothetical protein | 1 (bp 400) | 1 (E → K)a |
| NEIS1071 | Hypothetical protein | 1 (bp 461) | 1 (Y → C) |
| NEIS1383 (aroD) | Amino acid metabolism (phenylalanine, tyrosine and tryptophan biosynthesis) | 1 (bp 418) | 1 (V → M) |
| NEIS1605 | Enzyme (TatD DNase family) | 1 (bp 186) | 0 |
| NEIS1742 (murG) | Glycan metabolism/Vancomycin resistance | 1 (bp 632) | 1 (A → V) |
| NEIS2135 | Nicotinate and nicotinamide metabolism | 1 insertion (bp 155) | 15 stop codona |
aChange in the chemistry properties of the AA side chains