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. 2017 May 22;14:106. doi: 10.1186/s12974-017-0879-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Comparison of ChP cytokine-responsive genes (GO:0034097) after LPS challenge between genotypes. Expression levels were investigated by transcriptome analysis (Illumina HiSeq 2000) on RNA extracted from the choroid plexus. Transcripts of genes stimulated primarily by type I interferons increased in PrP^C-deficient goats compared with PRNP ^+/+ goats, whereas genes stimulated primarily by type II interferons were reduced. *Fold change ±1.2 and p < 0.05. n = 15