Figure 5.

Frequency of lipoarabinomannan (LAM)-responsive T cells in latent tuberculosis infection (LTBI) and posttuberculosis (post-TB) donors. Nonadherent peripheral blood mononuclear cells and autologous CD1⁺ antigen-presenting cells (3:1 ratio) were incubated with LAM (10 μg/ml). The frequency of CD3⁺IFN-γ⁺ T cells was determined after overnight incubation by intracellular flow cytometry. The figure presents the individual results of all donors tested. The P value (0.7751) was calculated using the Mann–Whitney U test for two-tailed samples. The horizontal bars represent the medians.