Table 2.

Regions showing a negative correlation with UPDRS subscales in the multiple regression analysis including all subscales.

Negative correlations	Anatomical region	Cluster size	Exact cluster p-value	T-value	MNI coordinates
UPDRS II	Bilateral: vermis 3–8, cerebellum 3–6 and crus 1 and 2, calcarine sulcus, superior occipital gyrus, fusiform gyrus, cuneus, precuneusRight: superior, middle and inferior temporal gyrus, Heschl gyrus, superior parietal lobule	4718	0.007	5.38∗	-12 -45 -12
UPDRS III	Bilateral: superior and middle frontal gyrus, supplementary motor area, anterior and middle cingulate gyrus, premotor cortex	2119	0.019	3.68	-9 27 33
UPDRS total	Bilateral: Vermis 4–8, cerebellum 4–8, cerebellar crus 1 and 2, putamen, pallidum and caudate nucleus, thalamus, posterior hippocampus and parahippocampal cortex, insula, inferior, middle and superior temporal gyrus and temporal pole, primary and supplementary motor cortex, paracentral lobule, primary sensory cortex, cuneus, precuneus, anterior and middle cingulate cortex, superior, middle and inferior frontal gyrus, superior medial frontal gyrus, triangular gyrus, superior parietal gyrus, fusiform gyrus, lingual gyrus, superior and inferior occipital gyrus Left: supramarginal gyrus, middle occipital gyrus, inferior parietal gyrus Right: operculum	15430	<0.001	5.12∗	-42 -66 -21

MNI, Montreal Neurological Institute space; UPDRS, Unified Parkinson’s Disease Rating Scale. ^∗Significant at a voxel-wise FWE corrected p < 0.05.