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. 2017 May 16;13(5):640–651. doi: 10.7150/ijbs.18636

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GFs coacervate administration inhibits excessive ERS in the DPN rats. (A) Sciatic nerve tissues samples were analyzed with Western Blotting for the expression of GRP-78, ATF-6, XBP-1, ATF-4, CHOP and Csapase-12. GAPDH was used for band density normalization. (B) The optical density analysis of GRP-78, ATF-6, XBP-1, ATF-4, CHOP and Csapase-12. ^*** P < 0.001 versus the control group, ^# P < 0.05, ^## P < 0.01, ^### P < 0.001 versus the STZ-diabetes group, ^&& P < 0.01, ^&&& P < 0.001 versus the free GFs group. Mean values ± SD, n=8. (C) Immunofluorescent staining of CHOP and caspase-12 in each group. Scale bars=50 μm.