Table 2.
Reasons for non-randomization among 208 patients with data available
| Reason | # Patients (%) (N = 208) | |
|---|---|---|
| Not NSCLC | 120 (57.7%) | |
|
| ||
| Benign | 104 (50.0%) | |
|
| ||
| Granuloma | 24 (11.5%) | |
|
| ||
| Hamartoma1 | 9 (4.3%) | |
|
| ||
| Infection | 11 (5.3%) | |
|
| ||
| Other2,3 | 60 (28.8%) | |
|
| ||
| Other malignancy | 16 (7.7%) | |
|
| ||
| Small cell lung cancer | 3 (1.4%) | |
|
| ||
| Carcinoid | 4 (1.9%) | |
|
| ||
| Lymphoma | 5 (2.4%) | |
|
| ||
| Metastatic, other site | 4 (1.9%) | |
|
| ||
| NSCLC but ineligible (more advanced) | 47 (22.6% of unrandomized, 10.7% of all registered NSCLC) | |
| Stage IA (T1b) | 6 | |
| Stage IIA | 6 | |
| Stage IIB | 6 | |
| Stage IIIA | 25 | |
| Stage IV (M1a) | 2 | |
| Unknown | 2 | |
|
| ||
| Positive nodes - (4) | 28 (13.5% of unrandomized, 6.4% of all registered NSCLC) | |
| N2 20 | ||
| N1 6 | ||
| Not specified 2 | ||
|
| ||
| Satellite nodule | 6 (2.9%) | |
|
| ||
| 2nd cancer in other lobe | 3 (1.4%) | |
|
| ||
| Pleural effusion | 2 (1.0%) | |
|
| ||
| Tumor > 2 cm | 6 (2.9%) | |
|
| ||
| Other (multiple lesions) | 2 (1.0%) | |
|
| ||
| Technical Reasons | 12 (5.8%) | |
|
| ||
| Unable to sample nodes | 3 (1.4%) | |
|
| ||
| Unsuitable for sublobar resection | 6 (2.9%) | |
|
| ||
| Hemorrhage | 1 (0.5%) | |
|
| ||
| Difficult anatomy | 2 (1.0%) | |
|
| ||
| Administrative/ Other/Unknown | 29 (13.9%) | |
|
| ||
| Patient refusal/withdrawal | 12 (5.8%) | |
|
| ||
| Surgeon decision | 7 (3.4%) | |
|
| ||
| Unknown | 10 (4.8%) | |
1
one was also unsuitable for wedge
2
one patient had eligible NSCLC but a suspected lymphoma in another lobe which turned out to be benign
3
Two cases of chronic inflammation, one each emphysema, inflammatory nodule, ischemic necrosis, scar tissue, sarcoidosis. Remainder unspecified.
4
one N2 case pathology was small cell