TABLE 1.

Activation Likelihood Estimation (ALE) Meta-Analyses Results for Social Tasks Comparing Participants With Autism-Spectrum Disorder (ASD) Versus Typically Developing Controls (TDC)

Analysis	Side	Brain Region	BA	Talairach			Cluster Size (MM3)	Extrema Value
				X	Y	Z
				ASD-child>TDC-child	L	Pre-central gyrus			6	−32	−12	60	376	0.01
	R	Temporal lobe	21	40	−4	−12	200	0.01
ASD-adult>TDC-adult	L	Superior temporal gyrus	41	−56	−24	6	312	0.01
TDC-child>ASD-child	R	Superior temporal gyrus	22	50	−14	−4	928	0.01
	R	Para-hippocampal gyrus/Amygdala		22	−10	−14	424	0.02
	L	Amygdala		−22	−8	−10	384	0.02
	R	Fusiform gyrus	19	28	−66	−4	368	0.02
	R	Superior temporal gyrus	22	48	−32	6	256	0.01
	L	Precentral gyrus	44	−50	14	10	256	0.01
	R	Culmen		24	−40	−14	216	0.01
TDC-adult>ASD-adult	L	Anterior cingulate	32	−4	42	−2	352	0.01
	L	Culmen		−34	−54	−24	304	0.01
Developmental Contrasts
Greater in ASD-child vs. ASD-adult	L	Post-central gyrus	3	−41	−22	55	64	1.80
	L	Post-central gyrus	2	−50	−24	50	40	1.80
Greater in ASD-adult vs. ASD-child		NS
Reduced in ASD-child vs. ASD-adult	R	Para-hippocampal gyrus/hippocampus		26	−11	−14	232	2.00
	R	Superior temporal gyrus	22	50	−13	0	128	1.96
	R	Superior temporal gyrus	22	44	−19	−9	64	2.03
Reduced in ASD-adult vs. ASD-child		NS

Note: BA = Brodmann area; L = left; NS = nonsignificant; R = right.