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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Crit Rev Oncol Hematol. 2017 Mar 14;113:71–78. doi: 10.1016/j.critrevonc.2017.03.011

Figure 4.

Figure 4

Hyperoxia or H2O2 treatment increases kallistatin expression in breast cancer cells. Hyperoxia (95% O2 and 5% CO2) treatment for 18 hr significantly increased kallistatin synthesis in (A) MCF-7 and (B) MDA-MB-231 breast cancer cells. H2O2 incubation (30 μM) for 12 hr also increased kallistatin synthesis in (C) MCF-7 and (D) MDA-MB-231 breast cancer cells. Kallistatin expression was blocked by the antioxidant N-acetyl-L-cysteine (NAC, 2 mM). n=3, *P<0.05 vs. other groups.