Table 1.
Descriptive background and echocardiographic data.
| All n = 368 | BAV n = 210 | TAV n = 158 | P-value BAV vs. TAV | |
|---|---|---|---|---|
| Age (years) | 64.3 ± 12.6 | 60.2 ± 12.2 | 69.5 ± 11.0 | < 0.001 |
| Height (m) | 1.74 ± 0.10 | 1.75 ± 0.09 | 1.72 ± 0.10 | 0.001 |
| BMI (kg/m2) | 26.9 ± 4.4 | 26.3 ± 4.2 | 27.5 ± 4.7 | < 0.05 |
| Inclusion SBP (mmHg) | 141 ± 20 | 139 ± 20 | 144 ± 20 | < 0.01 |
| Inclusion DBP (mmHg) | 80 ± 13 | 81 ± 12 | 77 ± 13 | 0.001 |
| Mean BP (mmHg) | 100 ± 12 | 101 ± 12 | 100 ± 13 | ns |
| Creatinine (μml/L) | 81 (70–91) | 80 (69–89) | 82 (70–92) | ns |
| hsCRP (mg/L) | 1.5 (0.6–3.1) | 1.1 (0.5–2.9) | 1.8 (0.8–3.6) | 0.001 |
| Triglycerides (mml/L) | 1.0 (0.8–1.5) | 1.0 (0.8–1.6) | 1.0 (0.7–1.5) | ns |
| Male gender | 245 (67%) | 148 (71%) | 97 (61%) | ns |
| Myocardial infarction | 20 (5%) | 6 (3%) | 14 (9%) | < 0.05 |
| Hypertension | 195 (53%) | 102 (49%) | 93 (59%) | < 0.05 |
| Echocardiographic data | ||||
| AoIMT (mm) | 1.37 ± 0.33 | 1.30 ± 0.33 | 1.44 ± 0.31 | < 0.001 |
| LVEDD (mm) | 52 ± 9 | 52 ± 9 | 52 ± 10 | ns |
| Pmax (mmHg) | 58 ± 37 | 62 ± 38 | 52 ± 26 | < 0.01 |
| AVA (cm2) | 1.6 ± 1.2 | 1.5 ± 1.1 | 1.7 ± 1.3 | < 0.05 |
| AR grade: 0/1/2/3 (%) | (23/44/12/21) | (24/44/13/18) | (20/44/12/25) | ns |
| Aorta ascendens/BSA (mm/m2) | 20 ± 5 | 20 ± 6 | 21 ± 5 | ns |
| Aorta descendens (mm) | 24 ± 3 | 23 ± 3 | 25 ± 3 | 0.001 |
| Aorta descendens/BSA (mm/m2) | 12 ± 2 | 12 ± 2 | 13 ± 2 | 0.001 |
BAV, bicuspid aortic valve; BMI, body mass index; hsCRP, high sensitivity C-reactive protein; TAV, tricuspid aortic valve; AoIMT, Aortic intima-media thickness; AVA, aortic valve area; LVEDD, left ventricular end-diastolic diameter; Pmax, aortic valve peak gradient; Values are expressed as mean ± SD, median and (25th–75th percentile) or as n (%) or %.