Figure 2.

Inhibition of hGGT1 by DON. (A) hGGT1 was preincubated at 37°C with 10 mM (closed circles), 5 mM (closed squares), 2.5 mM (closed triangles), 1.25 mM (inverted closed triangles) or 0 mM DON (open diamonds) for the time indicated. Immediately following the preincubation, the enzyme was assayed for activity. Data points are average of mean values for four experiments ± standard error. For some data points the error bars are smaller than the symbol. (B) The data for the inactivation of hGGT1 by DON were first‐order.