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. 2017 Mar 19;5(3):269–279. doi: 10.1002/mgg3.283

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© 2017 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Patients by metabolizer phenotype or warfarin dosing recommendations. A total of 94 patients were evaluated for PGx variant alleles by Baylor Genetics as part of clinical WES testing. The metabolizer phenotypes were interpreted from the variant alleles reported for (A) CYP2C19 (NG_008384.2; NC_000010.10; NM_000769.2; Build GRCh37.p13) and (B) CYP2C9 (NG_008385.1; NC_000010.10; NM_000771.3; Build GRCh37.p13), and the suggested warfarin dosing recommendations for the (C) combined interpretation of CYP2C9 and VKORC1 (NG_011564.1; NC_000016.9; NM_024006; Build GRCh37.p13) according to CPIC guidelines. The *1 allele was inferred in the absence of a reported variant allele. Current medication use was abstracted from the EMR.