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. 2017 May 23;3(2):00110-2016. doi: 10.1183/23120541.00110-2016

FIGURE 2.

FIGURE 2

PD-1 expression on CD8+ T-cells. a) Representative examples of PD-1 expression on CD8+ T-cells in peripheral blood mononuclear cells (PBMCs) and tumour-draining lymph nodes (TDLNs). b) Percentages of PD-1 (p<0.0001) and PD-1 mean fluorescence intensity levels on CD8+ T-cells present in PBMCs and TDLNs (p<0.05). c) Percentages of proliferating Ki67+ CD8+ T-cells in PBMCs and TDLNs (p<0.05). d) Pearson correlations between total percentages of PD-1+ cells on activated regulatory T-cells (aTreg) and CD8+ T-cells, activated (act)CD4+ T-cells and cytokine-secreting (cyt)CD4+ T-cells for the six TDLN samples in which we could evaluate aTreg frequencies.