Fig. 4.

Enzymatic activity of human d-aspartate oxidase (hDDO) in the dorsolateral prefrontal cortex (DLPFC) and hippocampus (Hipp.) of patients with schizophrenia (SCZ) and control (Ctrl) subjects. DDO enzymatic activity is analyzed a between the two diagnosis groups (DLPFC: Ctrl, n = 20; SCZ, n = 20−hippocampus: Ctrl, n = 20; SCZ, n = 19), and b between the two brain regions (Ctrl: DLPFC, n = 20; hippocampus, n = 20−SCZ: DLPFC, n = 20; hippocampus, n = 20). The enzymatic activity of DDO is expressed as μU/mg of total proteins. **p < 0.01, ***p < 0.0001 (Mann–Whitney test). Dots represent the single subjects’ values while bars illustrate the means ± SEM