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. 2017 Apr 13;3:18. doi: 10.1038/s41537-017-0019-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Disorganization Index classifies negative symptoms severity and schizophrenia diagnosis 6 months in advance. a Multiple linear correlation between PANSS negative subscale vs. Disorganization Index from dream + negative image reports, from negative image reports, or from dream reports (R ² and p value indicated on title; linear coefficients used to calculate Disorganization Index on Results). b Bar plot of the mean and standard error of Disorganization Index from dream + negative image reports, from negative image reports, or from dream reports for diagnostic groups (schizophrenia in red, bipolar in blue and control in black; bar plots indicate of median values and error bars indicate s.e.m; Kruskal–Wallis tests (Bonferroni corrected for 6 comparisons (2 memory reports asterisk 3 groups)): p value indicated in each title; # indicates p < 0.0063—Schizophrenia > Bipolar and Control groups; asterisk indicates p < 0.0063—Schizophrenia > Bipolar or Control groups). c Classification quality using only Disorganization Index from dream + negative image reports, from negative image reports, or from dream reports (measured by AUC and Accuracy—classification of schizophrenia diagnosis 6 months in advance (black); Negative Symptom Severity measured by PANSS negative subscale (gray). d Validation of the Disorganization Index using dream reports from an independent cohort of chronic psychotic patients.⁹ Multiple linear correlation between PANSS negative subscale vs. Disorganization Index (R ² and p value indicated on title; linear coefficients used to calculate Disorganization Index on Results), statistical comparison (schizophrenia in red, bipolar in blue and control in black; Kruskal–Wallis tests: p value indicated in each title; # indicates p < 0.0063—Schizophrenia > Bipolar and Control groups; asterisk indicates p < 0.0063—Schizophrenia > Bipolar or Control groups) or classification quality (measured by AUC and Acc—classification of schizophrenia diagnosis 6 months in advance (black); Negative Symptom Severity measured by PANSS negative subscale (gray))