Table 2.
A2 recipient characteristics from 1997 to 2007
| Recipient characteristics | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| A2 to A | A2 to AB | A2 to O | A2 to B | Total | p-value | |
| Mean age of recipient – yr (SD) | 49 (15) | 47 (16.1) | 42 (15.8) | 50 (13.2) | 49 (15.1) | <0.001 |
| Gender of recipient | ||||||
| Male (%) | 775 (58.7) | 40 (50.6) | 65 (52.0) | 74 (63.8) | 934 (58.2) | 0.141 |
| Race of recipient | ||||||
| White (%) | 832 (64.7) | 43 (54.4) | 99 (79.2) | 55 (47.4) | 1029 (64.1) | <0.001 |
| Black (%) | 269 (20.9) | 24 (30.4) | 12 (9.6) | 35 (30.2) | 340 (21.2) | |
| Other (%) | 185 (14.4) | 12 (15.2) | 14 (11.2) | 26 (22.4) | 237 (14.8) | |
| HLA match (%) | ||||||
| 0 | 187 (14.5) | 8 (10.1) | 11 (8.8) | 28 (24.1) | 234 (14.6) | <0.001 |
| 1 | 324 (25.2) | 24 (30.4) | 26 (20.8) | 41 (35.3) | 415 (25.8) | |
| 2 | 270 (21.0) | 16 (20.3) | 16 (12.8) | 32 (27.6) | 334 (20.8) | |
| 3 | 252 (19.6) | 13 (16.5) | 48 (38.4) | 12 (10.3) | 325 (20.2) | |
| 4 | 109 (8.5) | 7 (8.9) | 15 (12.0) | 3 (2.6) | 134 (8.3) | |
| 5 | 86 (6.7) | 6 (7.6) | 4 (3.2) | 0 | 96 (6.0) | |
| 6 | 55 (4.3) | 5 (6.3) | 3 (2.4) | 0 | 63 (3.9) | |
| HCV (%) | 68 (5.3) | 8 (10.1) | 2 (1.6) | 6 (5.2) | 84 (5.2) | 0.264 |
| Number of previous kidneys (%) | ||||||
| 0 | 1159 (90.1) | 62 (78.5) | 113 (90.4) | 103 (88.8) | 1437 (89.5) | 0.021 |
| 1 | 117 (9.1) | 16 (20.3) | 11 (8.8) | 13 (11.2) | 157 (9.8) | |
| ≥2 | 10 (0.8) | 1 (1.3) | 1 (0.8) | 0 | 12 (0.7) | |
| Delayed graft function (%) | 337 (26.2) | 15 (19) | 8 (6.4) | 25 (21.6) | 385 (24) | <0.001 |
| Diabetes (%) | 381 (29.6) | 34 (43) | 34 (27.2) | 41 (35.3) | 490 (30.5) | 0.046 |
| Peak PRA – mean (SD) | 16.0 (29.3) | 22.8 (35.4) | 13.81 (26.8) | 9.31 (21.1) | 15.7 (29.1) | 0.018 |
| Average wait time – d | ||||||
| All A2 (SD) | 575 (602) | 399 (444) | 337 (328) | 542 (548) | 552 (586) | <0.001 |
| Deceased donor A2 (SD) | 587 (417) | 405 (234) | 360 (280) | 540 (568) | 572 (392) | <0.001 |
| All ABO compatiblea (SD) | 494 (518) | 382 (432) | 684 (657) | 734 (521) | 606 (615) | <0.001 |
| Deceased donor ABO compatible (SD) | 583 (555) | 417 (456) | 832 (693) | 907 (721) | 726 (654) | <0.001 |
| Induction immunosuppressionb,c % | 54 | 57 | 55 | 67 | 55 | 0.147 |
| Discharge immunosuppressionb | ||||||
| Tacrolimus % | 45 | 43 | 37 | 57 | 45 | <0.001 |
| Cyclosporine % | 44 | 38 | 49 | 38 | 45 | |
| Mycophenolate % | 60 | 58 | 57 | 80 | 57 | |
| Imuran % | 28 | 35 | 31 | 19 | 34 | |
| Rapamycin % | 5 | 2 | 8 | 6 | 5 | |
| Rejection within 1 yr (%) | 179 (13.9) | 8 (10.1) | 11 (8.8) | 14 (11.2) | 212 (13) | 0.325 |
HCV, hepatitis C virus; PRA, panel reactive antibody.
a
Wait time for recipients of ABO compatible kidneys for blood groups A, AB, O and B, respectively.
b
Percentage of A2 recipients that immunosuppression data were reported, missing data for 40.1% of recipients.
c
Induction with either OKT3, Thymoglobulin, Simulect or Campath.