Table 1.
Two-way repeated measures ANOVA statistics for atlas based segmentation analysis using absolute volumes for each brain region measured. Maternal immune activation (MIA, [POL]) treatment served as between-subject factor and time as within-subject factor. aPost-hoc tests were only performed for significant age × MIA interactions using Bonferroni’s post-hoc test corrected for multiple comparisons. ANOVA, analysis of variance; MIA, maternal immune activation n.s., not significant.
| Brain region | Two way repeated measures ANOVA |
Post-hoc test (Bonferroni’s test for multiple comparisons)a | ||
|---|---|---|---|---|
| Within subjects |
Between groups | |||
| Age | Age × MIA interaction | MIA | ||
| Whole brain | F(2,7) = 13.87; p < 0.001 | F(2,7) = 0.12; n.s. | F(1,7) = 0.04; n.s. | None performed |
| Lateral ventricles | F(2,7) = 14.84; p < 0.001 | F(2,7) = 6.09; p < 0.05 | F(1,7) = 6.56; p < 0.05 | P180 SAL vs. P180 POL; p < 0.01 |
| Anterior cingulate cortex | F(2,7) = 15.43; p < 0.001 | F(2,7) = 3.78; p < 0.05 | F(1,7) = 5.00; n.s. | P90 SAL vs. P90 POL; p < 0.05 |
| Corpus striatum | F(2,7) = 44.72; p < 0.001 | F(2,7) = 1.16; n.s. | F(1,7) = 3.07; n.s. | None performed |
| Dorsal hippocampus | F(2,7) = 19.64; p < 0.001 | F(2,7) = 0.18; n.s. | F(1,7) = 10.52; p < 0.05 | None performed |
| Ventral hippocampus | F(2,7) = 28.13; p < 0.001 | F(2,7) = 0.33; n.s. | F(1,7) = 6.53; p < 0.05 | None performed |