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. 2017 May 23;12(5):e0176182. doi: 10.1371/journal.pone.0176182

Fig 2. Effects of MK-2305 on oral glucose tolerance in GK rats.

Fig 2

(A) Blood glucose time course in GK rats treated acutely with MK-2305, followed by an OGTT. (B) AUC data for glucose vs. time post-challenge data in (A). (C) Plasma insulin vs. time data for the OGTT shown. (D) Plasma insulin AUC data for the OGTT. Statistical comparisons of AUC for glucose or insulin across treatment groups were compared via ANOVA followed by Dunnetts post hoc analysis where MK-2305 treated groups were compared to vehicle. ***p<0.001.