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. 2017 Apr 26;114(19):4993–4998. doi: 10.1073/pnas.1705327114

Fig. S3.

Fig. S3.

Distribution of T-cell subsets and PD-1 expression on NSCLC patients and healthy subjects. Analysis was performed in whole blood obtained from NSCLC patients before PD-1–targeted therapy initiation. Healthy volunteers were recruited through Emory Vaccine Center. (A) Graphs show frequency of CCR7+CD45RA+ naïve (N), CCR7+CD45RAneg central memory (TCM), CCR7negCD45RAneg effector memory (TEM), and CCR7negCD45RA+ effector memory RA (TEMRA) on CD8 T cells (Left) and CD4 T cells (Right). (B) Graphs show frequency of PD-1+ T cells among the different subsets described in A, on CD8 T cells (Left) and CD4 T cells (Right). Gates were established based on naïve T cells. Lines represent the median. Unpaired Student t test.