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. 2017 Apr 24;114(19):E3776–E3785. doi: 10.1073/pnas.1702251114

Fig. 1.

Fig. 1.

Structure of Myo7b CMF/USH1C PDZ3 complex. (A) Schematic diagrams showing the domain architectures of Myo7b and USH1C. The interaction is mediated by Myo7b CMF and USH1C PDZ3. The color coding of the domains is kept throughout the report. (B) Ribbon representation (Left) and schematic cartoon diagram (Right) of the Myo7b CMF/USH1C PDZ3 complex structure. The disordered loops are drawn as dashed lines in the ribbon representation. (C) Surface representation of the Myo7b CMF structure showing the central pocket. The USH1C PDZ3 domain is shown as ribbon, and its C-terminal tail is shown as stick and transparent spheres. The amino acid sequence of the USH1C C-terminal tail is shown below the surface diagram. (D) Ribbon representation (Left) and schematic cartoon diagram (Right) of the Myo7a NMF/USH1G CEN and Myo7b NMF/ANKS4B CEN complexes. (E) Ribbon representation (Left) and schematic cartoon diagrams (Right) of the Myo10 MF/DCC complex.