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. 2017 Apr 26;114(19):E3839–E3848. doi: 10.1073/pnas.1608769114

Fig. S2.

Fig. S2.

Complement C3 and mediators of C3′s effects are up-regulated in the ONH during very early stages of glaucoma. Genes up-regulated include C3 itself, the C3 convertase Cfb, and receptors for C3 fragments C3a (C3ar1) and C3b (Itgb2 and Itgax).