Fig. S3.

Expression of selected clock-controlled transcriptional outputs in human lung as determined by CYCLOPS. Using independent biopsy datasets (21) from the University of Groningen (Groningen, The Netherlands) and the University of Laval (Quebec City, QC, Canada), we used CYCLOPS to generate two reconstructions of the circadian transcriptome in the human lung. Expression data from human homologs of genes found to be cycling in mouse lung (1) were used in the ordering. Expression data for the labeled transcripts are plotted as a function of CYCLOPS phase. CYCLOPS-ordered expression data from Groningen are plotted in blue. CYCLOPS-ordered expression data from Quebec City are plotted in green.