FIG. 13.

Sequence alignment of Rv0774c and Rv0519c (proposed mycolyltransferase II) with FbpA, FbpB, and FbpC (mycolyltransferases). At the top of the alignments, active-site residues Ser, Asp/Glu, and His are indicated by asterisks. Multiple-sequence alignments were obtained with the Clustal W program (version 1.8) (106), and the resulting alignment was refined manually. Black shading indicates residues identical to those in mycolyltransferases; gray shading indicates residues similar to those in mycolyltransferases. For better visualization, the first 78 residues of Rv1288 are not included in the alignment, because none of them matched in the comparison.