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. 2017 May 2;114(20):5183–5188. doi: 10.1073/pnas.1614838114

Fig. 3.

Fig. 3.

Speed–accuracy trade-off in aa-tRNA selection by three varieties of E. coli ribosome. One is the wild-type (WT). The other two are hyperaccurate (HYP) and more error-prone (ERR) mutants. (A) ητ curves for the GTP hydrolysis step. The actual system (green circle, WT) is situated close to the minimum τ (yellow square) and far away from minimum η (red triangle); this is also true for the mutants. (B) Speed–accuracy trade-off for the ternary complex binding step. The minimum error is achieved in the k1,R0 limit. MFPTs for all of the systems are close to saturation.