. Author manuscript; available in PMC: 2018 Apr 1.

Published in final edited form as: J Biomed Inform. 2017 Mar 8;68:150–166. doi: 10.1016/j.jbi.2017.03.003

Table 3.

Retrieval and reapplication of relational structure with PSI. Data, derivation and presentation as in Table 2. Up to five results >= 4SD above the mean of ( $1 - \frac{2 \times hamming distance}{dimensionality}$ ) are shown. ASSOC=ASSOCIATED_WITH.

Cue	Target	Results	Comments
S(haloperidol) ⊘ C(schizophrenia)	Predicate vectors	8.16: TREATS	Haloperidol is a treatment for schizophrenia.
S(haloperidol) ⊘ S(schizophrenia)	Products of predicate vector pairs	6.74: COMPARED WITH-INV ⊘ TREATS-INV 4.53: INTERACTS WITH ⊘ ASSOC-INV	Haloperidol has been compared with another drug that schizophrenia is treated by, and interacts with a biological entity that is associated with schizophrenia.
S(docetaxel) ⊘ P(COMPARED WITH-INV) ⊗ P(TREATS-INV)	Semantic vectors	14.79:non-small_cell lung_cancer_recurrent 13.58:small_cell lung_cancer_recurrent 12.35:non_small_cell lung_cancer_metastatic 11.27:oesophageal adenocarcinoma_stage_iii 9.7034:esophageal neoplasm_metastatic	Applying a two-predicate path inferred from haloperidol::schizophrenia to docetaxel returns potential therapeutic applications of this drug.