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. 2017 Apr 11;19(5):597–604. doi: 10.1093/ntr/ntx001

Table 4.

Comparison Between Nonsmokers’ and Starters’ Sibling Pair Groups

First sibling Second sibling total
n % per 1000 n % per 1000
Any psychiatric diagnosis
 Starters 1051 21.4 10.7 1224 24.9 12.5 4918
 Nonsmokers 18 139 15.6 7.7 19 807 17.0 8.5 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 1.47 1.37–1.58
 Adjusted OR (95% CI) 1 1.39 1.30–1.49
Any psychiatric diagnosis in inpatient care
 Starters 379 7.7 3.7 470 9.6 4.6 4918
 Nonsmokers 5683 4.9 2.3 6745 5.8 2.8 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 1.63 1.46–1.81
 Adjusted OR (95% CI) 1 1.40 1.27–1.55
Any psychiatric diagnosis in outpatient care
 Starters 846 17.2 8.5 1 157 23.5 11.9 4918
 Nonsmokers 14 117 12.1 5.9 18 697 16.1 7.9 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 1.51 1.40–1.62
 Adjusted OR (95% CI) 1 1.38 1.29–1.48
Externalizing psychiatric diagnosis
 Starters 394 8.0 3.8 448 9.1 4.3 4918
 Nonsmokers 4650 4.0 1.9 5127 4.4 2.1 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 2.09 1.88–2.33
 Adjusted OR (95% CI) 1 1.68 1.51–1.87
Externalizing psychiatric diagnosis in inpatient care
 Starters 61 1.2 0.6 51 1.0 0.5 4918
 Nonsmokers 631 0.5 0.3 570 0.5 0.2 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 2.30 1.77–3.00
 Adjusted OR (95% CI) 1 1.66 1.23–2.24
Externalizing psychiatric diagnosis in outpatient care
 Starters 333 6.8 3.2 397 8.1 3.8 4918
 Nonsmokers 4019 3.5 1.6 4557 3.9 1.8 116 391
The second sibling in nonsmokers The second sibling in starters
 Crude OR (95% CI) 1 2.03 1.81–2.28
 Adjusted OR (95% CI) 1 1.66 1.49–1.86

CI = confidence interval; OR = odds ratio. “Smoking in neither pregnancy” referred as nonsmokers and “Smoking only in the second pregnancy” as starters.