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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Prog Retin Eye Res. 2017 Jan 19;58:70–88. doi: 10.1016/j.preteyeres.2017.01.005

Figure 8. EZRIN immunolabeling in WT, BVMD, and ARB hiPSC-RPE.

Figure 8

(A-C) Immunohistochemical analysis of WT hiPSC-RPE showed strong expression of EZRIN with vertically oriented, apical localization. (D-F) Similar expression and localization of EZRIN was observed in BVMD hiPSC-RPE. (G-I) In the ARB hiPSC-RPE, harboring compound heterozygous mutation in BEST1, MV are smaller in height compared to the WT hiPSC-RPE, and express EZRIN in a punctate fashion within a thin apical band. XZ and YZ labeled images are representative images for X-Z and Y-Z optical sections. Scale bar: 10µm applies to all panels.