Table 1.

Population characteristics of participating cohorts

Race	Characteristics		ARIC	Health ABC	ROS/MAP ADGC	ROS/MAP CHOP
AA	N		1053	769	86	71
	Age at assessment (years), mean ± SD		74.95 ± 5.09	75.44 ± 2.83	81.75 ± 5.51	72.37 ± 7.69
	Men,%		351 (33.33)	326 (42.39)	38 (43.18)	11 (15.49)
	Smell identification score, mean ± SD		7.97 ± 2.61	8.71 ± 2.54	8.68 ± 2.39	8.97 ± 2.01
	Cognitive score, mean ± SD
	MMSE		25.17 ± 3.77	-	27.77 ± 2.19	27.93 ± 2.29
	MMMSE		-	85.32 ± 10.54	-	-
	APOE genotypes, (%)
	22		16 (1.56)	8 (1.04)	1 (1.14)	0 (0)
	23		145 (14.13)	123 (15.99)	15 (17.05)	8 (11.27)
	24		54 (5.26)	40 (5.20)	7 (7.95)	6 (8.45)
	33		474 (46.20)	362 (47.07)	46 (52.27)	33 (46.48)
	34		298 (29.04)	214 (27.83)	15 (17.05)	23 (32.39)
	44		39 (3.80)	22 (2.86)	3 (3.41)	1 (1.41)
			ARIC	Health ABC	ROS/MAP batch 1	ROS/MAP batch 2
EA	N		3985	1311	998	288
	Age at assessment (years), mean ± SD		75.89 ± 5.18	75.69 ± 2.82	82.29 ± 6.71	81.46 ± 7.02
	Men,%		1751 (43.94)	691 (52.71)	277 (27.76)	72 (25.00)
	Smell identification score, mean ± SD		9.50 ± 2.30	9.51 ± 2.12	8.54 ± 2.48	9.02 ± 2.55
	Cognitive score, mean ± SD
	MMSE		27.89 ± 2.28	-	27.94 ± 2.52	27.83 ± 2.72
	MMMSE		-	92.88 ± 5.92	-	-
	APOE genotypes, (%)
	22		27 (0.71)	9 (0.69)	6 (0.60)	2 (0.69)
	23		515 (13.52)	164 (12.51)	153 (15.33)	37 (12.85)
	24		87 (2.28)	21 (1.60)	17 (1.70)	4 (1.39)
	33		2307 (60.58)	822 (62.70)	617 (61.82)	189 (65.63)
	34		817 (21.45)	278 (21.21)	189 (18.94)	52 (18.06)
	44		55 (1.44)	17 (1.30)	16 (1.60)	4 (1.39)

AA: African-Americans; EA: European-Americans; ARIC: the Atherosclerosis Risk in Communities study; Health ABC: the Health, Aging, and Body Composition study; ROS/MAP: the Rush Religious Orders Study (ROS) and Memory and Aging Project (MAP); MMSE: Mini-Mental State Examination, range of possible score 0–30; MMMSE: Modified Mini Mental Status Examination, range of possible score 0–100; SD: standard deviation.

For ApoE, numbers do not add up to total due to missing values.