Table 2.
Relationship between hemostasis abnormalities predisposing to thrombosis and SCD phenotypes
Patients N (%) | Controls N (%) | P | |
---|---|---|---|
S/S phenotype | |||
PC deficiency | 15 (46.87) | 1 (1.66) | 0.000 |
PS deficiency | 17 (53.12) | 1 (1.66) | 0.000 |
AT deficiency | 9 (28.12) | 0 (0.00) | 0.000 |
FVIIIc increase | 31 (96.87) | 4 (6.66) | 0.000 |
S/β thalassemia phenotype | |||
PC deficiency | 7 (35) | 1 (1.66) | 0.000 |
PS deficiency | 7 (35) | 1 (1.66) | 0.000 |
AT deficiency | 0 (0.00) | 0 (0.00) | * |
FVIIIc increase | 8 (40) | 4 (6.66) | 0.000 |
S/A phenotype | |||
PC deficiency | 2 (6.89) | 1 (1.66) | 0.200 |
PS deficiency | 1 (3.44) | 1 (1.66) | 0.595 |
AT deficiency | 0 (0.00) | 0 (0.00) | * |
FVIIIc increase | 9 (31.03) | 4 (6.66) | 0.002 |
PC protein C, PS protein S, AT antithrombin
* No statistics are computed because AT is a constant