TABLE 2.
Nucleotide sequence variation in Legionella pneumophila gene fragments
| Locus | Putative function of gene product | Size of sequenced fragment (bp) | No. of identified alleles | No. of polymorphic sites | No. of synonymous polymorphic sites | dS/dNa | GenBank accession no. |
|---|---|---|---|---|---|---|---|
| acn | Aconitase | 427 | 17 | 22 | 16 | 18.8 | L22081 |
| rpoB | RNA polymerase β, subunit | 419 | 14 | 26 | 18 | 1.42 | AF087812 |
| asd | Aspartate-β-semialdehyde dehydrogenase | 473 | 15 | 19 | 16 | 1.29 | AF034213 |
| mip | Macrophage infectivity potentiator | 402 | 15 | 14 | 11 | NAb | AF023173 |
| mompS | Outer membrane surface protein | 485 | 17 | 35 | 27 | 11.25 | AF078136 |
a
dS, synonymous base substitutions per site; dN, nonsynonymous base substitutions per site. dS/dN was calculated with the SNAP program.
b
NA, not analyzed. The dS/dN could not be calculated for the mip gene because the proportion of synonymous or nonsynonymous substitutions was ≥0.75 in some alleles, and the Jukes-Cantor transformation could not be applied.