TABLE 1.

Toxicity of Cry11A toward C. quinquefasciatus selected or nonselected with Cry11A from B. thuringiensis subsp. israelensis for 20 generations

Mosquito straina	Toxin tested	Generation	LC50 (μg/ml), FLb	LC95 (μg/ml), FL	Resistance ratio at:
					LC50	LC95
SynParent	Cry11A	4	1.65, 0.255-9.68	624, 59.4-7,574	1.0	1.0
Cry11A	Cry11A	4	3.00, 1.63-4.74	990, 519-2,431	1.8	1.6
SynParent	Cry11A	7	1.57, 0.805-3.05	129, 38.8-436	1.0	1.0
Cry11A	Cry11A	7	8.49, 5.25-13.6	425, 173-1,103	5.4	3.3
SynParent	Cry11A	9	7.33, 4.73-11.3	332, 136-834	1.0	1.0
Cry11A	Cry11A	9	15.7, 12.1-20.1	2,048, 1,201-3,953	2.1	6.2
SynParent	Cry11A	13	4.20, 2.32-7.59	244, 78.2-789	1.0	1.0
Cry11A	Cry11A	13	103, 73.6-150	58,253, 21,190-∞	24.5	238
SynParent	Cry11A	17	0.885, 0.329-2.35	57.7, 11.9-285	1.0	1.0
Cry11A	Cry11A	17	91.8, 59.4-152	511,705, 101,376-∞	103	8,862
SynParent	Cry11A	20	3.60, 1.73-7.45	3,686, 709-20,488	1.0	1.0
Cry11A	Cry11A	20	1,358, 664-4,104	456,127, 476,570-∞	377	1,237

^aSynParent, unselected; Cry11A, Cry11A selected.

^bFL, fiducial limits.